Publication & Presentation 発表実績
2025（令和７年）
(2024 Journal Impact Factor = 8.9, Q1 journal)
Takanori Eguchi, Stuart K. Calderwood. Discovery of myeloid zinc finger (MZF) 1 nuclear bodies. Biochemical and Biophysical Research Communications 2025;752:1511481
(2023 Journal Impact Factor = 2.5)
Tanai A, Fukuhara Y, Eguchi T, Kawai H, Ueda K, Ochiai K, Ikegame M, Okamoto K, Okamura H. P. gingivalis–Infected Macrophage Extracellular Vesicles Cause Adverse Pregnancy Outcomes. Journal of Dental Research 2025;104(1):54-63.
(2024 Journal Impact Factor = 5.9, Q1 journal)
Presentations 学会発表等
江口傑徳，エマン・タハ，中野敬介，ヴィカス・ティワリ，武部克希，岡元邦彰，スチュアート・カルダーウッド．癌の予後を予測するバイオマーカーの開発．第46回岡山歯学会学術集会．2025年11月30日．
Eguchi T, Taha E, Nakano K, Tiwari V, Takebe K, Okamoto K, and Calderwood SK. Development of biomarkers for predicting cancer prognosis. The 46th annual meeting of the Okayama Dental Society. November 30th, 2025.
Xu H, Yamamoto Y, Yamayoshi M, Kamada H, Naruse K, Eguchi T, and Takahashi K. Development of a Microfluidic Cancer Chip to Investigate Tumor–Immune Cell Communication via Extracellular Vesicles. 第48回日本生体医工学会中国四国支部大会．2025年11月8日．
江口傑徳, 陸彦因, 吉田国弘, 武部克希, 岡元邦彰．転移性頭頸部癌が分泌するマトリックス被覆細胞外小胞．第12回日本細胞外小胞学会学術集会．大阪，2025年10月14～15日．Eguchi T, Lu Y, Yoshida K, Takebe K, and Okamoto K. Laminin beta3 identifies matrix-coated extracellular vesicles in pre-metastatic head and neck squamous cell carcinomas.
李雪鳴，武部克希，吉田国弘，土佐郁恵，江口傑徳，大原直也，岡元邦彰 細胞内小胞輸送タンパク質RAB11を介した微小管の不安定化．第67回歯科基礎医学会．2025年9月5日〜7日．北九州
Li Xueming, Katsuki Takebe, Kunihiro Yoshida, Ikue Tosa, Takanori Eguchi, Naoya Ohara, Kuniaki Okamoto. Dynamic instability of microtubules through intracellular transport protein RAB11 in oral cancer. The 67th Annual Meeting of the Japanese Association for Oral Biology.
Xueming Li, Katsuki Takebe, Kuniaki Okamoto. Involvement of intracellular transport protein Rab11 in cancer malignancy. 第43回創薬・薬理フォーラム岡山．2025年7月5日．広島
Tanai A, Fukuhara Y, Yao W, Ueda K, Eguchi T, Ikegame M, Ibaragi S, Okamura H. P. gingivalis-OMVs compromise placental angiogenesis and fetal development. The 52nd Annual Meeting of the Japanese Society of Toxicology. Okinawa, July, 2025. 棚井あいり, 福原瑶子, 翁瑤, 植田幸嗣，江口傑徳，池亀美華，伊原木聰一郎, 岡村裕彦. P. gingivalisの細胞外小胞は胎盤形成および胎児の成長を阻害する. 沖縄, 2025年7月.
2024（令和６年）
Review Articles 総説
江口傑徳. エクソソーム. 岡山医学会雑誌 2024,136(1):33-36
Takanori Eguchi. Exosome. Journal of Okayama Medical Association 2024 Apr,136(1):33-36
Joshua A Welsh*, Deborah C.I. Goberdhan*, Lorraine O'Driscoll*, Edit I Buzas et al, MISEV Consortium, Takanori Eguchi et al, Clotilde Thery*, Kenneth W Witwer*. Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches. Journal of Extracellular Vesicles, 2024 Feb;13(2):e12404. doi: 10.1002/jev2.12404.
(2022 Journal Impact Factor = 16.0) Q1 journal in cell biology, 2017-
Enormous citations
Matthias P. Mayer*, Blair L, Blatch GL, Borges TJ, Chadli A, Chiosis G, de Thonel A, Dinkova-Kostova A, Ecroyd H, Edkins AL, Takanori Eguchi, Fleshner M, Kevin P. Foley, Fragkostefanakis S, Gestwicki J, Goloubinoff P, Heritz JA, Heske CM, Hibshman JD, Jenny Joutsen, Li P, Lynes M, Marc L. Mendillo, Mivechi N, Mokoena F, Yuka Okusha, Prahlad V, Repasky E, Sannino S, Scalia F, Shalgi R, Sistonen L, Sontag E, van Oosten-Hawle P, Vihervaara A, Wickramaratne A, Wang SXY, Zininga T. Stress Biology: Complexity and Multifariousness in Health and Disease. Cell Stress and Chaperones, 2024, Feb;29(1):143-157. DOI: 10.1016/j.cstres.2024.01.006
(2022 Journal Impact Factor = 3.8)
Original Articles 原著論文
Htike K, Yoshida K, Eguchi T, Takebe K, Li X, Qu Y, Sakai E, Tsukuba T, Okamoto K. A Herbal medicine Ninjinyoeito inhibits RANKL-induced osteoclast differentiation and bone resorption activity by regulating NF-κB and MAPK pathway. J Oral Biosci. 2024 Dec;66(4):49-57.
(2023 Journal Impact Factor = 2.6, Q1 journal)
Novel mechanism of cisplatin resistance in head and neck squamous cell carcinoma involving extracellular vesicles and a copper transporter system. Head Neck. 2024 Mar;46(3):636-650. doi: 10.1002/hed.27620. Epub 2024 Jan 2.
(2022 Journal Impact Factor = 2.9) Q1 journal in Otorhinolaryngology, 2021-)
Kunihiro Yoshida, Kaung Htike, Takanori Eguchi, Hotaka Kawai, Htoo Shwe Eain, Manh Tien Tran, Chiharu Sogawa, Koki Umemori, Tatsuo Ogawa, Hideka Kanemoto, Kisho Ono, Hitoshi Nagatsuka, Akira Sasaki, Soichiro Ibaragi, Kuniaki Okamoto*.
Rab11 Suppresses Head and Neck Carcinoma by Regulating EGFR and EpCAM Exosome Secretion. Journal of Oral Biosciences 2024 Mar;66(1):205-216. doi: 10.1016/j.job.2023.11.007. Epub 2023 Dec 10.
(2022 Journal Impact Factor = 2.4) Q1 journal in dentistry, oral surgery & medicine, 2022.
Presentations in meetings 学会発表等
カウン・タイッ，吉田国弘，江口傑徳，武部克希，坂井詠子，筑波隆幸，岡元邦彰 人参養栄湯はNF-kB経路を介して破骨細胞分化や骨吸収を抑制する．第66回歯科基礎医学会学術大会，2024年11月2日〜4日，長崎
Htike K, Yoshida K, Eguchi T, Takebe K, Sakai E, Tsukuba T, Okamoto K Herbal medicine Ninjinyoeito (人参養栄湯) inhibits RANKL-induced osteoclast differentiation and bone resorptive activity by regulating NF-kB pathway. The 66th Annual Meeting of Japanese Association for Oral Biology.
Yanyin Lu, Kunihiro Yoshida, Lizi Xing, Katsuki Takebe, Kisho Ono, Mona Sheta, Kuniaki Okamoto, Hongyu Yang, Takanori Eguchi. 27th Congress of the European Association for Cranio Maxillo Facial Surgery (EACMFS) Abstract reference number #626, Poster, Category: Cancer biology and epidemiology. Rome, Sept,2024.
伊藤菜々穂, 吉田国弘, 岡元邦彰, 江口傑徳．オートファジー及びミトコンドリアを標的とした口腔癌シスプラチン耐性解除．第67回歯科基礎医学会学術大会, 長崎, 2025年11月2日～4日. Targeting autophagy and mitochondria to overcome cisplatin resistance in oral cancer. The 66th Annual Meeting of Japanese Association for Oral Biology.
Itoh N, Okamoto Y, Takebe K, Okamoto K, Eguchi T. Targeting autophagy and mitochondria to overcome cisplatin resistance in oral cancer. Japan Dental Association Student Clinician Research Program (SCRP). English Oral Presentation, August, 6th, 2024.
伊藤菜々穂，(ファカルティアドバイザー：江口傑徳, 共同研究者： 岡本侑太郎, 研究指導協力者：武部克希，岡元邦彰)．オートファジー及びミトコンドリアを標的とした口腔癌シスプラチン耐性解除. 令和6年度日本歯科医師会スチューデント・クリニシャン・リサーチ・プログラム（SCRP）日本代表選抜大会，英語口演，2023年8月6日. 第3位受賞.
武部克希．第19回FMODD全体会議・FMODD10周年記念シンポジウム．ポスター発表．大阪,2024年5月8日〜9日．
Lizi Xing, Kunihiro Yoshida, Ken Takahashi, Nanaho Itoh, Yutaro Okamoto,Yui Yamamoto, Hotaka Kawai, Kuniaki Okamoto, Takanori Eguchi. Roles of Extracellular Vesicles in tumoroid and tumor microenvironment. 7th International Student Research Presentation 第7回外国人留学生研究発表会.岡山 2024/3/7
Mona Sheta, Kunihiro Yoshida, Eman A. Taha, Kuniaki Okamoto, Takanori Eguchi. Extracellular Vesicles (EVs) as a Drug Carrier for Targeting Cancer Metabolism Kinase. 7th International Student Research Presentation. Okayama, March,2024. Excellent presentation award.
モナ･シータ, 吉田国弘, エマン･タハ, 岡元邦彰, 江口傑徳. 癌代謝キナーゼを標的とする薬物キャリアとしての細胞外小胞. 第7回外国人留学生研究発表会. 岡山．2024/3/7．優秀発表賞受賞
2023（令和５年）
Review Articles 総説
Mona Sheta, Eman A. Taha, Yanyin Lu, Takanori Eguchi*. Extracellular vesicles: new classification and tumor immunosuppression.
Biology (Basel) 2023, 12(1):110.
(2021 Journal Impact Factor = 5.168) Q1 journal in biology, 2019 - 2021
Top 1% article
Original Article 原著論文
Mona Sheta, Kunihiro Yoshida, Hideka Kanemoto, Stuart K Calderwood, Takanori Eguchi*. Stress-Inducible SCAND Factors Suppress the Stress Response and Are Biomarkers for Enhanced Prognosis in Cancers. International Journal of Molecular Sciences 2023, 24(6):5168.
(2022 Journal Impact Factor = 5.6) Q1 journal in biochemistry & molecular biology, 2019 - 2022
EpEX, the soluble extracellular domain of EpCAM, resists cetuximab treatment of EGFR-high head and neck squamous cell carcinoma.
Oral Oncology 2023, 142:106433
(2022 Journal Impact Factor = 4.8) Q1 Journal in Dentistry, Oral Surgery & Medicine, 2000 - 2021. Q1 Journal in Oncology, 2017 - 2021)
Book Chapters 著書
Andrew Ackerman, Toshiki Kijima, Takanori Eguchi, Thomas Prince* (2023) Monitoring of the heat shock response with a real-time luciferase reporter. In: Calderwood S.K., Prince T.L.(eds) Chaperones. Methods Molecular Biology, vol 2693. Humana, New York, NY, pp.1-11. First Online: 05 August 2023. Springer Nature Experiments, Springer Protocols 2023.
Kisho Ono, Takanori Eguchi* (2023) Multiple targeting of HSP isoforms to challenge isoform specificity and compensatory expression. In: Calderwood S.K., Prince T.L.(eds) Chaperones. Methods Molecular Biology, vol 2693. Humana, New York, NY, pp.141-161. First Online: 05 August 2023. Springer Nature Experiments, Springer Protocols 2023.
Top 10% article
Kisho Ono, Takanori Eguchi* (2023) Proteomic profiling of the extracellular vesicle chaperone in cancer. In: Calderwood S.K., Prince T.L.(eds) Chaperones. Methods Molecular Biology, vol 2693. Humana, New York, NY, pp.233-249. First Online: 05 August 2023. Springer Nature Experiments, Springer Protocols 2023.
Hotaka Kawai, Kisho Ono, Takanori Eguchi* (2023) Multiplex immunostaining method to distinguish HSP isoforms in cancer tissue specimens. In: Calderwood S.K., Prince T.L.(eds) Chaperones. Methods Molecular Biology, vol 2693. Humana, New York, NY, pp.281-291. First Online: 05 August 2023. Springer Nature Experiments, Springer Protocols 2023.
Kisho Ono, Takanori Eguchi* (2023) Large-scale databases and portals on cancer genome to analyze chaperone genes correlated to patient prognosis. In: Calderwood S.K., Prince T.L.(eds) Chaperones. Methods Molecular Biology, vol 2693. Humana, New York, NY, pp.293-306. First Online: 05 August 2023. Springer Nature Experiments, Springer Protocols 2023.
Top 10% article
岡本侑太朗, 伊藤菜々穂（指導教員：江口傑徳，岡元邦彰，ティーチングアシスタント：吉田国弘, Mona Sheta）. ミトコンドリア分子阻害およびオートファジー阻害による頭頸部癌抑制とシスプラチン耐性解除の試み.岡山大学歯学部自由研究演習報告書. 2023.12.15受理
Lecture and Symposium (講演、シンポジウム)
Takanori Eguchi, Mona Sheta, Hotaka Kawai, Kunihiro Yoshida, Eva Csizmadia, Barbara Wegiel, Thomas L. Prince, Stuart K. Calderwood. Extracellular Vesicle HSPs and SCAN Transcription Factors in cancer (Role of Zinc finger transcription factors in regulating molecular chaperone expression). Session 1: Chaperone gene transcription. The 2nd International Symposium on the Chaperone Code & 12th International Symposium on Heat Shock Proteins in Biology and Medicine. Old town,VA,USA. October 29, 2023.Invited
江口傑徳,青山絵理子,滝川正春. オンコ知新 ーヒト軟骨肉腫細胞株のRNA-seq解析－ 日本CCN研究会 シンポジウム,岡山,2023/9/2
Takanori Eguchi, Eriko Aoyama, Masaharu Takigawa. Learn from the oldoncology, know the new: RNA-seq analysis of human chondrosarcoma-derived cells. Japan CCN Family Study Group, Symposium. 2023/9/2
Presentations in domestic meetings 国内学会発表等
岡本侑太郎、伊藤菜々穂（指導教員： 江口 傑徳、岡元 邦彰、ティーチングアシスタント：吉田 国弘、Mona Sheta）オートファジー阻害剤による頭頚部癌抑制の検討 (ミトコンドリア分子阻害およびオートファジー阻害による頭頸部癌抑制とシスプラチン耐性解除の試み) 自由研究演習(研究室配属)･歯学国際交流演習(ODAPUS)発表会．2023/12/8
Yanyin Lu, Kunihiro Yoshida, Takanori Eguchi. Intracellular and extracellular proteolysis by vesicular metalloproteinase in cancer. International vesicle meeting, Okayama, 2023.11.28.
モナ・シータ，吉田国弘, 岡元邦彰, 江口傑徳 癌代謝キナーゼを標的とする薬物キャリアとしての細胞外小胞．第17回日本臨床ストレス応答学会, 2023年11月17日〜18日, 徳島. Mona Sheta, Kunihiro Yoshida, Kuniaki Okamoto, Takanori Eguchi. Extracellular Vesicles as a Drug Carrier for Targeting Cancer Metabolism Kinase. The Biomedical Society for Stress Response Japan, Annual Meeting.
吉田国弘，小野喜章，河合穂高，梅森洸樹，金本栄華，小川辰雄，竜門省二，伊原木聰一郎．(非会員協力者： 岡元邦彰、江口傑徳).頭頸部癌におけるSmall GTPase Rab11の機能解析. 第68回(公社)日本口腔外科学会総会・学術大会．2023年11月10日～12日,大阪．
Mona Sheta, Kunihiro Yoshida, Kuniaki Okamoto, Takanori Eguchi. Discovery and targeting of metabolism kinase in cancer organoid EVs. 癌オルガノイド由来細胞外小胞に含まれる癌代謝キナーゼの発見とその分子標的．第10回日本細胞外小胞学会. 2023/10/23,24, 札幌.
Takanori Eguchi, Mona Sheta, Kunihiro Yoshida, Kisho Ono. Extracellular Vesicle Kinases Secreted by Metastatic Cancer Organoids.
The 82nd Annual Meeting of the Japanese Cancer Association, English Oral Session. Yokohama, 2023/9/22. 江口傑徳, モナ・シータ, 吉田国弘, 小野喜章. 転移性癌オルガノイドから分泌される細胞外小胞キナーゼ. 第82回日本癌学会学術総会. 英語口演セッション. 横浜, 2023/9/22.
Mona Sheta, Kunihiro Yoshida, Eman A. Taha, Kuniaki Okamoto, Takanori Eguchi. Extracellular Vesicles (EVs) as a Drug Carrier for Targeting Cancer Metabolism Kinase. Brainstorming 2023, Okayama. 2023/8/26. Best Presentation Award Received. モナ・シータ、吉田国弘、タハ・A・エマン、岡元邦彰、江口傑徳. 癌代謝キナーゼを標的とする薬物のキャリアとしての細胞外小胞. ブレインストーミング2023, 岡山. 2023/8/26. 最優秀発表賞受賞.
吉田国弘，カウン・タイッ，河合穂高，伊原木聰一郎，岡元邦彰. 頭頸部癌の遊走および浸潤における Rab11 の役割. 第39回創薬・薬理フォーラム岡山．2023年7月22日．
2022（令和４年）
Review Article 総説
Takanori Eguchi*, Mona Sheta, Masanori Fujii, Stuart K. Calderwood.
Cancer Extracellular Vesicles, Tumoroid Models and Tumor Microenvironment.
Seminars in Cancer Biology 2022,86(Pt 1):112-126
(2021 Journal Impact Factor = 17.012) Q1 journal in oncology
Top 3% Article
Original Article 原著論文
Takanori Eguchi*, Eva Csizmadia, Hotaka Kawai, Mona Sheta, Kunihiro Yoshida, Thomas L. Prince, Barbara Wegiel, Stuart K. Calderwood. SCAND1 Reverses Epithelial-to-Mesenchymal Transition (EMT) and Suppresses Prostate Cancer Growth and Migration
Cells 2022,11(24),3993
(2021 Journal Impact Factor = 7.666) Q2 journal in cell biology, 2019-
JCI Insight, 2022, 7(1); e148960
(2021 Journal Impact Factor = 9.533) Q1 Journal in medicine, research & experimental, 2017-.
Top 4% article
Manh Tien Tran, Yuka Okusha, Kaung Htike, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto*. HSP90 drives the Rab11a‐mediated vesicular transport of the cell surface receptors in osteoclasts.
Cell Biochemistry and Function 2022, 40(3):835-855
(2021 Journal Impact Factor = 3.963) Q3 journal in biochemistry & molecular biology, Q3 journal in cell biology
Yunxia Feng, Manh Tien Tran, Yanyin Lu, Kaung Htike, Yuka Okusha, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto*. Rab34 plays a critical role as a bi-directional regulator of osteoclastogenesis.
Cell Biochemistry & Function 2022, 40(3):263-277
(2021 Journal Impact Factor = 3.963) Q3 journal in biochemistry & molecular biology, Q3 journal in cell biology
Book Chapters 著書
Top 2% article
Top 10% article
Top 10% article
Top 2% article
Presentations in international meetings 国際学会発表等
Airi Tanai, Yoko Fukuhara, Takanori Eguchi, Koji Ueda, Mika Ikegame, Hirohiko Okamura. Porphyromonas gingivalis-infected Macrophage Extracellular Vesicles And Pregnancy. 2022 AADOCR/CADR Annual Meeting & Exhibition, Atlanta, March, 2022. SCRP日本代表
Presentations in domestic meetings 国内学会発表等
Kaung Htike, Kuniaki Okamoto. Herbal medicine Ninjinyoeito (人参養栄湯) inhibits RANKL-induced osteoclast differentiation and bone resorptive activity by regulating NF-kB pathway. 創薬・薬理フォーラム岡山, Web開催，2022年12月24日. 口演
江口傑徳 (Takanori Eguchi). がんのストレス抵抗性に関わるMZF核ボディの構造解析. 第16回日本臨床ストレス応答学会大会, Web開催. 2022年11月6日. 口演
Takanori Eguchi, Benjamin Lang, Mona Sheta, Manh Tien Tran, Barbara Wegiel, Stuart Calderwood (江口傑徳, ベンジャミン・ラング, モナ・シータ, マン・チャン, バーバラ・ヴェンゲル, スチュアート・カルダーウッド). SCAND1 and MZF1 co-regulate epithelial-to-mesenchymal transition in cancer (転写因子MZF1とSCAND1による相反的なEMT制御). 第81回日本癌学会学術総会, 横浜, 2022年10月1日. 英語口演
河合穂高, 冨田秀太, 江口傑徳, 大原利章, 小野喜章, 長塚仁 (Hotaka Kawai, Shuta Tomida, Takanori Eguchi, Toshiaki Ohara, Kisho Ono, Hitoshi Nagatsuka). 口腔癌間質細胞由来CCL2による骨髄由来細胞動員への関与 (Resident stroma-secreted chemokine CCL2 governs myeloid-derived suppressor cells in the tumor microenvironment). 第81回日本癌学会学術総会, 横浜, 2022年10月1日. ポスター発表
奥舎有加, エマン・タハ, 陸 彦因, モナ・シータ, 河合穂高, 十川千春, 岡元邦彰, 江口傑徳 (Yuka Okusha, Eman A. Taha, Yanyin Lu, Mona Sheta, Hotaka Kawai, Chiharu Sogawa, Kuniaki Okamoto, Takanori Eguchi). 細胞外小胞に搭載されたムーンライティングMMPによるマトリックス制御と転移促進 (Metalloproteinase on Extracellular Vesicles Regulates ECM in Tumor Microenvironment and Promotes Invasion and Metastasis). 第81回日本癌学会学術総会, 横浜, 2022年9月30日. ポスター発表
奥舎有加，江口傑徳，Manh T. Tran，十川千春，吉田賀弥，板垣まみ，Eman A. Taha，小野喜章，青山絵理子, 岡村裕彦，小崎健一，Stuart K.Calderwood，滝川正春，岡元邦彰. 高転移性癌細胞由来の細胞外小胞に搭載されたMMP3 によるCtgf/Ccn2 発現調節機能と癌転移促進．第64回歯科基礎医学会学術大会.2022年9月18日. 日本歯科基礎医学会奨励賞受賞口演.
Okusha Y, Eguchi T, Tran MT, Sogawa C, Yoshida K, Itagaki M, Taha EA, Ono K, Aoyama E, Okamura H, Kozaki K, Calderwood SK, Takigawa M, Okamoto K. Extracellular vesicles enriched with moonlighting metalloproteinase are highly transmissive, Pro-tumorigenic, and trans-activates cellular communication network factor（CCN2/CTGF)：CRISPR against cancer.
森綾乃，山本直史，江口傑徳，高柴正悟．侵襲性歯周炎の血液診断マーカー候補となる細胞外小胞由来マイクロRNAとその炎症誘導機構の探索．Proinflammatory Mechanism Regulated by Circulating Extracellular Vesicles-derived microRNAs: Potential Diagnostic Biomarkers for Aggressive Periodontitis. 第65回秋季日本歯周病学会学術大会. 2022年9月2日.
山本結，高橋賢，岡元邦彰，江口傑徳．癌チップの独自開発と口腔癌の免疫抵抗性の発見，Brainstorming-2022 (12th)，岡山，2022年8月．
山本結，(研究指導協力者：高橋賢，岡村裕彦，岡元邦彰，ファカルティアドバイザー：江口傑徳)．癌チップの独自開発と口腔癌の免疫抵抗性の発見. 令和4年度日本歯科医師会スチューデント・クリニシャン・リサーチ・プログラム（SCRP）日本代表選抜大会，英語口演，Web開催，2022年8月．令和4年度SCRP優秀賞受賞. Yamamoto Y, Takahashi K, Okamura H, Okamoto K, Eguchi T. Original development of cancer chip and discovery of immunoresistance in oral cancer. 2022 JDA Student Clinician Research Program. English Oral Presentation, Online, August 2022.
河合 穂高, メイ・ワトウ, 高畠 清文, 冨田 秀太, 小野 喜章, 江口 傑徳, 大原 利章, 中野 敬介, 長塚 仁. 口腔癌間質由来のCCL2はCCR2陽性骨髄由来免疫抑制細胞の腫瘍間質への動員に関与する. 第26回日本がん免疫学会総会. 2022年7月20-22日.
2021（令和３年）
Original Articles 原著論文
Yanyin Lu, Takanori Eguchi*, Chiharu Sogawa, Eman A. Taha, Manh Tien Tran, Toshiki Nara, Penggong Wei, Shiro Fukuoka, Takuya Miyawaki, Kuniaki Okamoto. Exosome-Based Molecular Transfer Activity of Macrophage-Like Cells Involves Viability of Oral Carcinoma Cells: Size Exclusion Chromatography and Concentration Filter Method. Cells 2021,10(6):1328
(2021 Journal Impact Factor =7.666) Q2 journal in cell biology, 2019-
Cells 2021,10(2):344
(2021 Journal Impact Factor =7.666) Q2 journal in cell biology, 2019-
Top 6% article
Manh Tien Tran, Yuka Okusha, Yunxia Feng, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto*. A novel role of HSP90 in regulating osteoclastogenesis by abrogating Rab11b-driven transport. Biochimica et Biophysica Acta - Molecular Cell Research 2021,868(10):119096
(2020 Journal Impact Factor =4.739) Q2 journal in biochemistry & molecular biology, 2019-
Kadowaki T, Yamaguchi Y, Ogawa K, Tokuhisa M, Okamoto K, Tsukuba T. Rab44 isoforms similarly promote lysosomal exocytosis, but exhibit differential localization in mast cells. FEBS Open Bio 2021,11(4):1165-1185.
(2020 Journal Impact Factor =2.693) Q4 journal in biochemistry & molecular biology
山本結,(指導教員: 江口傑徳、高橋賢、岡元邦彰, ティーチングアシスタント: 陸彦因、福岡史朗). Cancer-on-a-chip： 蛍光エクソソーム技術とマイクロ流体チップを用いた腫瘍-単球コミュニケーションモデルの構築. 岡山大学歯学部自由研究演習(研究室配属)報告書. 2021年12月.
小林直生,(指導教員：江口傑徳、高橋賢、岡元邦彰, 研究協力者：陸彦因、福岡史郎)．Bone-on-a-chip: 蛍光エクソソーム技術とマイクロ流体チップを用いたマクロファージ-骨芽細胞コミュニケーションモデルの構築．岡山大学歯学部自由研究演習(研究室配属)報告書. 2021年12月.
Review Articles 総説
Stuart K. Calderwood, Thiago J. Borges, Takanori Eguchi, Benjamin J. Lang, Ayesha Murshid, Yuka Okusha, Thomas L. Prince.
Extracellular Hsp90 and Protection of Neuronal Cells Through Nrf2. Biochemical Society Transactions 49(5):2299-2306, 2021.
(2021 Journal Impact Factor = 4.919) Q2 journal in biochemistry & molecular biology, 2019-
Book Chapters 著書
None
Presentations 学会発表等
福岡史朗, 江口傑徳, 陸彦因, 上原健敬, 藤原智洋, 中田英二, 尾﨑敏文, 岡元邦彰. 細胞外小胞を利用した新規骨再生療法の検討. 第36回創薬・薬理フォーラム岡山．2021年12月25日．
江口傑徳．エクソソームに搭載される多機能タンパク質：HSP90とMMP3．第15回日本臨床ストレス応答学会大会．大阪，2021年11月
陸 彦因，江口傑徳．マクロファージ由来のHSP90搭載エクソソームは口腔癌細胞への効率的な分子送達能と細胞毒性を有す．第15回日本臨床ストレス応答学会大会，大阪，2021年11月
小野喜章，江口傑徳，十川千春，奥舎有加，岡元邦彰，佐々木朗．口腔癌のエクソソームを介した腫瘍進展機序の解明と新規治療戦略の開発に向けて 〜分子シャペロン搭載エクソソームの可能性〜．第57回日本口腔組織培養学会学術大会．Web開催（三重大学主催），2021年11月．
棚井あいり、福原瑶子、江口傑徳、植田幸嗣、吉田賀弥、岡村裕彦．歯周病原菌に感染したマクロファージ由来の細胞外小胞は胎盤の血管形成を阻害する．第8回日本細胞外小胞学会，WEB開催，2021年10月
棚井あいり, 福原瑶子, 江口傑徳, 河合穂高, 池亀美華, 岡村裕彦, 植田幸嗣. Porphyromonas gingivalisはマクロファージの細胞外小胞を介して胎盤・胎児の成長発育を阻害する(Porphyromonas gingivalis impairs placental and fetal development through macrophage-derived extracellular vesicles). 第63回歯科基礎医学会学術大会, オンライン開催（神奈川歯科大学主催），2021年10月
棚井あいり，(研究指導協力者：福原瑤子，江口傑徳, 池亀美華，ファカルティアドバイザー：岡村裕彦)．歯周病と胎児の成長障害：Porphyromonas gingivalisはマクロファージの細胞外小胞を介して胎盤の血管形成を阻害する. 令和3年度日本歯科医師会スチューデント・クリニシャン・リサーチ・プログラム（SCRP）日本代表選抜大会，英語口演，Web開催，2021年8月．令和3年度SCRP優勝
Tanai A, Fukuhara Y, Eguchi T, Ikewgame M, Okamura H. Periodontitis & abnormal pregnancies: Porphyromonas gingivalis utilizes macrophage extracellular vesicles and inhibits placental angiogenesis. 2021 JDA Student Clinician Research Program. English Oral Presentation, Online, August 2022.
山本結,(指導教員: 江口傑徳、高橋賢、岡元邦彰, ティーチングアシスタント: 陸彦因、福岡史朗). Cancer-on-a-chip： 蛍光エクソソーム技術とマイクロ流体チップを用いた腫瘍-単球コミュニケーションモデルの構築. 岡山大学歯学部自由研究演習(研究室配属)発表会. 2021年12月.
小林直生,(指導教員：江口傑徳、高橋賢、岡元邦彰, 研究協力者：陸彦因、福岡史郎)．Bone-on-a-chip: 蛍光エクソソーム技術とマイクロ流体チップを用いたマクロファージ-骨芽細胞コミュニケーションモデルの構築．岡山大学歯学部自由研究演習(研究室配属)発表会. 2021年12月.
2020（令和２年）
Original Articles 原著論文
(2020 Journal Impact Factor = 25.841) Q1 journal in cell biology, 2017-
Top 2% Article
Takanori Eguchi*, Chiharu Sogawa, Kisho Ono, Masaki Matsumoto, Manh Tien Tran, Yuka Okusha, Benjamin J. Lang, Kuniaki Okamoto, Stuart K. Calderwood. Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells. Cells 2020, 9(3):755
(2020 Journal Impact Factor =6.600) Q2 journal in cell biology, 2019-
Top 4% Article
Yuka Okusha, Takanori Eguchi*, Manh Tien Tran, Chiharu Sogawa, Kaya Yoshida, Mami Itagaki, Eman A Taha, Kisho Ono, Eriko Aoyama, Hirohiko Okamura, Ken-ichi Kozaki, Stuart K Calderwood, Masaharu Takigawa, Kuniaki Okamoto. Extracellular Vesicles Enriched with Moonlighting Metalloproteinase are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer. Cancers (Basel) 2020, 12(4):881
(2020 Journal Impact Factor =6.639) Q1 journal in oncology, 2017-
Top 7% Article
Eman A Taha, Chiharu Sogawa, Yuka Okusha, Hotaka Kawai, May Wathone Oo, Abdellatif Elseoudi, Yanyin Lu, Hitoshi Nagatsuka, Satoshi Kubota, Ayano Satoh, Kuniaki Okamoto, Takanori Eguchi*. Knockout of MMP3 weakens solid tumor organoids and cancer extracellular vesicles. Cancers (Basel) 2020, 12(5):1260
(2020 Journal Impact Factor =6.639) Q1 journal in oncology, 2017-
Top 7% Article
Chiharu Sogawa, Takanori Eguchi*, Manh Tien Tran, Masayuki Ishige, Kilian Trin, Yuka Okusha, Eman A. Taha, Yanyin Lu, Hotaka Kawai, Norio Sogawa, Masaharu Takigawa, Stuart K. Calderwood, Kuniaki Okamoto, Ken-ichi Kozaki. Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3. Cancers (Basel) 2020, 12(2):523.
(2020 Journal Impact Factor =6.639) Q1 journal in oncology, 2017-
Top 10% Article
Yuka Okusha, Manh Tien Tran, Masayuki Itagaki, Chiharu Sogawa, Takanori Eguchi, Tatsuo Okui, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto*. Rab11A Functions as a Negative Regulator of Osteoclastogenesis through Dictating Lysosome-Induced Proteolysis of c-fms and RANK Surface Receptors. Cells 2020, 9(11):2384
(2020 Journal Impact Factor = 6.600) Q2 journal in cell biology, 2019-
Manh Tien Tran, Yuka Okusha, Yunxia Feng, Masatoshi Morimatsu, Penggong Wei, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Hirohiko Okamura, Keiji Naruse, Takayuki Tsukuba, Kuniaki Okamoto*. The Inhibitory Role of Rab11b in Osteoclastogenesis through Triggering Lysosome-Induced Degradation of c-Fms and RANK Surface Receptors. International Journal of Molecular Sciences 2020, 21(24):9352
(2020 Journal Impact Factor =5.923) Q1 journal in biochemistry & molecular biology, 2019-
Mariko Seyama, Kaya Yoshida, Kayo Yoshida, Natsumi Fujiwara, Kisho Ono, Takanori Eguchi, Hotaka Kawai, Jiajie Guo, Yao Weng, Yuan Haoze, Kenta Uchibe, Mika Ikegame, Akira Sasaki, Hitoshi Nagatsuka, Kuniaki Okamoto, Hirohiko Okamura, Kazumi Ozaki.
Outer membrane vesicles of Porphyromonas gingivalis attenuate insulin sensitivity by delivering gingipains to the liver.
Biochimica et Biophysica Acta – Molecular Basis of Disease 2020, 1866(6):165731
(Journal Impact Factor =4.328) Q1 journal in biochemistry & molecular biology, 2020-. Q1 journal in biophysics, 2007-
Top 4% Article
Review Articles 総説
Takanori Eguchi*, Eman A. Taha, Stuart K. Calderwood, Kisho Ono. A Novel Model of Cancer Drug Resistance: Oncosomal Release of Cytotoxic and Antibody-Based Drugs. Biology (Basel) 2020, 9(3):47
(2020 Journal Impact Factor =5.079) Q1 journal in biology, 2019-
Takanori Eguchi*. Organoids and Liquid Biopsy in Oral Cancer Research. Journal of Clinical Medicine 2020, 9(11):3701
(2020 Journal Impact Factor =4.241) Q1 journal in medicine, general & internal, 2020
Book Chapters 著書
Takanori Eguchi*, Eman A. Taha (2020). Extracellular Vesicle-Associated Moonlighting Proteins: Heat Shock Proteins and Metalloproteinases. In: Asea, A.A.A., Kaur, P. (eds) Heat Shock Proteins in Inflammatory Diseases. Heat Shock Proteins, vol 22. Springer Nature, Cham, Switzerland, pp.1-18
Tadashi Yamamoto*, Takanori Eguchi* (2020). Heat Shock Proteins and Periodontitis ― Cross-Reaction Between Bacterial and Human HSP in Periodontal Infection Linking with Cardiovascular Diseases. In: Asea, A.A.A., Kaur, P. (eds) Heat Shock Proteins in Inflammatory Diseases. Heat Shock Proteins, vol 22. Springer Nature, Cham, Switzerland, pp.19-32
Yanyin Lu, Takanori Eguchi* (2020). HSP Stimulation on Macrophages Activates Innate Immune System. In: Asea, A.A.A., Kaur, P. (eds) Heat Shock Proteins in Inflammatory Diseases. Heat Shock Proteins, vol 22. Springer Nature, Cham, Switzerland, pp.53-67
Kazuyuki Furuta*, Takanori Eguchi* (2020). Roles of Heat Shock Proteins on Antigen Presentation. In: Asea, A.A.A., Kaur, P. (eds) Heat Shock Proteins in Human Diseases. Heat Shock Proteins, vol 21. Springer Nature, Cham, Switzerland, pp.275-280
Symposium シンポジウム
江口傑徳，十川千春，岡元邦彰．オルガノイドと細胞外小胞を癌研究に応用する．シンポジウム テーマ：発生と疾患にみる新たな細胞間コミュニケーション，第62回日本歯科基礎医学会，鹿児島（Web開催），2020年9月．
江口傑徳. 三次元腫瘍オルガノイドの開発と細胞外小胞の新機能．シンポジウム テーマ：顎口腔領域の発生と疾患に見る細胞間情報伝達機構の新たなカタチ, 第125回日本解剖学会全国学術集会，宇部（誌上開催），2020年3月．
江口傑徳. 中枢神経作用薬に見出した抗癌作用 ～独創的研究を志して～, 岡山大学歯学部第14期生卒後20周年記念同窓会 記念講演，岡山，2020年2月．
Presentations in international and domestic meetings 国際学会発表 国内学会発表等
河本美奈, 山本直史, 河村麻理, 森綾乃, 山城圭介, 大森一弘, 小野喜章，江口傑徳, 十川千春, 高柴正悟. 侵襲性歯周炎の血液診断バイオマーカーとしての細胞外小胞由来マイクロRNAの探索．第41回岡山歯学会，誌上発表，2020年10月．
Abdellatif El-Seoudi, Tarek Abd El Kader, Takashi Nishida, Takanori Eguchi, Eriko Aoyama, Takako Hattori, Masaharu Takigawa, Satoshi Kubota. Effects of Fibroblast Growth Factor 1 (FGF-1) on CCN2 Gene Expression in Chondrocytic Cells, Experimental Biology 2019 (EB2019) Annual Meeting, San Diego, United States, April, 2020.
十川千春，江口傑徳，Tran Tien Manh，石毛真行，河合穂高，奥舎有加，中野敬介，十川紀夫，小崎健一，岡元邦彰. パーキンソン病治療薬の抗癌作用（ドラッグリポジショニングの提案）. 第45回岡山脳研究セミナー，岡山，2020年1月．
2019（令和元年）
Review Articles 総説
Eman A. Taha, Kisho Ono, Takanori Eguchi*. Roles of Extracellular HSPs as Biomarkers in Immune Surveillance and Immune Evasion.
International Journal of Molecular Sciences 2019, 20(18):4588.
(2019 Journal Impact Factor =4.556) Q1 journal in biochemistry & molecular biology, 2019-
Top 2% Article
> 150 citations
Original Articles 原著論文
Takanori Eguchi*, Thomas L. Prince, Manh Tien Tran, Chiharu Sogawa, Benjamin J. Lang, Stuart K. Calderwood. MZF1 and SCAND1 Reciprocally Regulate CDC37 Gene Expression in Prostate Cancer. Cancers (Basel) 2019, 11(6):792
(2019 Journal Impact Factor =6.162) Q1 journal in oncology
Chiharu Sogawa, Takanori Eguchi*, Yuka Okusha, Kisho Ono, Kazumi Ohyama, Motoharu Iizuka, Ryu Kawasaki, Yusaku Hamada, Masaharu Takigawa, Norio Sogawa, Kuniaki Okamoto, Ken-ichi Kozaki. A Reporter System Evaluates Tumorigenesis, Metastasis, β-catenin/MMP Regulation, and Druggability. Tissue Engineering Part A 2019, 25(19-20):1413-1425
(Journal Impact Factor =3.616) Q2 journal in cell biology, Q2 journal in engineering, biomedical
Saori Yoshida, Hotaka Kawai*, Takanori Eguchi*, Shintaro Sukegawa, May Wathone Oo, Chang Anqi, Kiyofumi Takabatake, Keisuke Nakano, Kuniaki Okamoto, Hitoshi Nagatsuka. Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer. Cells 2019, 8(7):761
(2020 Journal Impact Factor =6.600) Q2 journal in cell biology, 2019-
Reiko Shimizu, Soichiro Ibaragi*, Takanori Eguchi, Daisuke Kuwajima, Shinichi Kodama, Tsuyoshi Nishioka, Tatsuo Okui, Kyoichi Obata, Kiyofumi Takabatake, Hotaka Kawai, Kisho Ono, Kuniaki Okamoto, Hitoshi Nagatsuka, Akira Sasaki. Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma. International Journal of Oncology 2019, 54(1):283-294
(Journal Impact Factor =3.571) Q2 journal in oncology, 2012-
Book Chapter 著書
Takanori Eguchi*, Kisho Ono, Kazumi Kawata, Kuniaki Okamoto, Stuart K. Calderwood (2019). Regulatory Roles of HSP90-rich Extracellular Vesicles. In: Asea A., Kaur P.(eds) Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Proteins, vol 19, Springer Nature, Cham, pp.3-17.
2018年（平成30年）
Original Articles 原著論文
Kisho Ono, Takanori Eguchi*, Chiharu Sogawa, Stuart K. Calderwood, Junya Futagawa, Tomonari Kasai, Masaharu Seno, Kuniaki Okamoto, Akira Sasaki, Ken-ichi Kozaki. HSP-Enriched Properties of Extracellular Vesicles Involve Survival of Metastatic Oral Cancer Cells. Journal of Cellular Biochemistry 2018, 119(9):7363-76. (Journal Impact Factor =4.237) Q2 journal in biochemistry & molecular biology, 1997-. Q2 journal in cell biology, 2017-
> 150 citations
Top 2% Article
Yuka Okusha, Takanori Eguchi*, Chiharu Sogawa, Tatsuo Okui, Keisuke Nakano, Kuniaki Okamoto, Ken-ichi Kozaki. The Intranuclear PEX Domain of MMP Involves Proliferation, Migration, and Metastasis of Aggressive Adenocarcinoma Cells. Journal of Cellular Biochemistry 2018, 119(9):7350-62
(Journal Impact Factor =4.237) Q2 journal in biochemistry & molecular biology, 1997-. Q2 journal in cell biology, 2017-
Takanori Eguchi*, Chiharu Sogawa, Yuka Okusha, Kenta Uchibe, Ryosuke Iinuma, Kisho Ono, Keisuke Nakano, Jun Murakami, Manabu Itoh, Kazuya Arai, Toshifumi Fujiwara, Yuri Namba, Yoshiki Murata, Kazumi Ohyama, Manami Shimomura, Hirohiko Okamura, Masaharu Takigawa, Tetsuya Nakatsura, Ken-ichi Kozaki, Kuniaki Okamoto, Stuart K. Calderwood. Organoids with Cancer Stem Cell-like Properties Secrete Exosomes and HSP90 in a 3D Nanoenvironment. PLoS One 2018, 13(2):e0191109
(Journal Impact Factor =2.776) Q1 journal in multidisciplinary sciences, 2017-
> 100 citations
Top 3% Article
Toshifumi Fujiwara, Takanori Eguchi*, Chiharu Sogawa, Kisho Ono, Jun Murakami, Soichiro Ibaragi, Jun-ichi Asaumi, Stuart K. Calderwood, Kuniaki Okamoto, Ken-ichi Kozaki. Carcinogenic Epithelial-Mesenchymal Transition Initiated by Oral Cancer Exosomes is Inhibited by anti-EGFR Antibody Cetuximab. Oral Oncology 2018, 86:251-257.
(2018 Journal Impact Factor =3.730) Q1 journal in dentistry, oral surgery & medicine, 2000-. Q1 journal in oncology, 2017-
>100 citations
Top 4% Article
Toshifumi Fujiwara, Takanori Eguchi*, Chiharu Sogawa, Kisho Ono, Jun Murakami, Soichiro Ibaragi, Jun-ichi Asaumi, Kuniaki Okamoto, Stuart K. Calderwood, Ken-ichi Kozaki. Anti-EGFR Antibody Cetuximab is Secreted by Oral Squamous Cell Carcinoma and Alters EGF-Driven Mesenchymal Transition. Biochemical and Biophysical Research Communications 2018, 503(3):1267-72
(2018 Journal Impact Factor =2.705) Q2 journal in biochemistry & molecular biology, 2017-. Q2 journal in biophysics, 2017-
Top 9% article
Yuri Namba, Chiharu Sogawa, Yuka Okusha, Hotaka Kawai, Mami Itagaki, Kisho Ono, Jun Murakami, Eriko Aoyama, Kazumi Ohyama, Jun-ichi Asaumi, Masaharu Takigawa, Kuniaki Okamoto, Stuart K. Calderwood, Ken-ichi Kozaki, Takanori Eguchi*.
Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells. Frontiers in Oncology 2018, 8(376):1-16
(2018 Journal Impact Factor = 4.137) Q2 journal in oncology, 2017-
Top 6% article
Ara T, Nakatani S, Kobata K, Sogawa N, Sogawa C*. The Biological Efficacy of Natural Products against Acute and Chronic Inflammatory Diseases in the Oral Region. Medicines (Basel) 2018, 5(4):122.
Jianlin Gong, Benjamin J. Lang, Desheng Weng, Takanori Eguchi, Ayesha Murshid, Thiago J. Borges, Sachin Doshi, Baizheng Song, Mary Ann Stevenson, Stuart K. Calderwood. Genotoxic stress induces Sca-1-expressing metastatic mammary cancer cells.
Molecular Oncology 2018, 12(8):1249-63.
(JIF=5.962) Q1 journal in oncology, 2010-
Morisawa A, Okui T, Shimo T, Ibaragi S, Okusha Y, Ono M, Nguyen TTH, Hassan NMM, Sasaki A. Ammonium tetrathiomolybdate enhances the antitumor effects of cetuximab via the suppression of osteoclastogenesis in head and neck squamous carcinoma. International Journal of Oncology 2018, 52(3):989-999. Q2 journal in oncology, 2012-
Hasegawa K, Okui T, Shimo T, Ibaragi S, Kawai H, Ryumon S, Kishimoto K, Okusha Y, Monsur Hassan NM, Sasaki A. Lactate Transporter Monocarboxylate Transporter 4 Induces Bone Pain in Head and Neck Squamous Cell Carcinoma. International Journal of Molecular Sciences 2018, 19(11):3317.
Book Chapters 著書
Takanori Eguchi, Benjamin J. Lang, Ayesha Murshid, Thomas L. Prince, Jianlin Gong, Stuart K. Calderwood* (2018). Regulatory Roles for Hsp70 in Cancer Incidence and Tumor Progression. In Mario D. Galigniana (Ed.) Role of Molecular Chaperones in Structural Folding, Biological Functions, and Drug Interactions of Client Proteins. Frontiers in Structural Biology, Vol.1, Bentham Science Publishers, pp.1-22.
Toshiki Kijima, Takanori Eguchi, Len Neckers, Thomas L. Prince (2018). Monitoring of the Heat Shock Response with a Real-Time Luciferase Reporter. In Calderwood S., Prince T. (eds) Chaperones. Methods in Molecular Biology, vol 1709, Humana Press, New york, NY, pp.35-45.
2017（平成29年）
Original Articles 原著論文
Takanori Eguchi*, Stuart K. Calderwood, Masaharu Takigawa, Satoshi Kubota, Ken-ichi Kozaki. Intracellular MMP3 Promotes HSP Gene Expression in Collaboration with Chromobox Proteins. Journal of Cellular Biochemistry 2017, 118(1):43-51
(Journal Impact Factor = 4.237) Q2 journal in biochemistry & molecular biology, 1997-. Q2 journal in cell biology, 2017-
Kazumi Kawata, Satoshi Kubota, Takanori Eguchi, Eriko Aoyama, Norifumi H. Moritani, Morihiko Oka, Harumi Kawaki, Masaharu Takigawa. A tumor suppressor gene product, platelet-derived growth factor receptor-like protein controls chondrocyte proliferation and differentiation. Journal of Cellular Biochemistry 2017, 118(11):4033-44.
(Journal Impact Factor =4.237) Q2 journal in biochemistry & molecular biology, 1997-. Q2 journal in cell biology, 2017-
Hiroyuki Takada, Soichiro Ibaragi, Takanori Eguchi, Tatsuo Okui, Kyoichi Obata, Masanori Masui, Ayaka Morisawa, Kiyofumi Takabatake, Hotaka Kawai, Norie Yoshioka, Nur Mohammad Monsur Hassan, Tsuyoshi Shimo, Guo Fu Hu, Hitoshi Nagatsuka, Akira Sasaki.
Semaphorin 4D promotes bone invasion in head and neck squamous cell carcinoma. International Journal of Oncology 2017, 51(2):625-632.
(Journal Impact Factor =3.571) Q2 journal in oncology, 2012-
Abdellatif El-Seoudi, Tarek Abd El Kader, Takashi Nishida, Takanori Eguchi, Eriko Aoyama, Masaharu Takigawa, and Satoshi Kubota.
Catabolic effects of FGF-1 on chondrocytes and its possible role in osteoarthritis. Journal of Cell Communication and Signaling 2017, 11(3):255-263.
(Journal Impact Factor =3.691) Q2 journal in cell biology, 2018-
Nagata H, Kozaki KI, Muramatsu T, Hiramoto H, Tanimoto K, Fujiwara N, Imoto S, Ichikawa D, Otsuji E, Miyano S, Kawano T, Inazawa J. Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma.
Oncotarget 2017, 8(23):37740-37750.
Okusha Y, Hirai Y, Maezawa H, Hisadome K, Inoue N, Yamazaki Y, Funahashi M. Effects of intraperitoneally administered L-histidine on food intake, taste, and visceral sensation in rats. Journal of Physiological Science 2017, 67(4):467-474.
Book Chapter 著書
Takanori Eguchi*, Satoshi Kubota, Masaharu Takigawa (2017). Promoter Analyses of CCN Genes. In Takigawa M. (eds) CCN Proteins.
Methods in Molecular Biology, vol 1489, Humana Press, New York, NY. pp.177-185.
2016（平成28年）
Original Articles 原著論文
Kazuya Arai, Takanori Eguchi*, Mamunur M. Rahman, Ruriko Sakamoto, Norio Masuda, Tetsuya Nakatsura, Stuart K. Calderwood, Ken-ichi Kozaki, Manabu Itoh. A Novel High-Throughput 3D Screening System for EMT Inhibitors: a Pilot Screening Discovered the EMT Inhibitory Activity of CDK2 Inhibitor SU9516. PLoS One 2016, 11(9):e0162394
(Journal Impact Factor =3.234) Q1 journal in multidisciplinary sciences, 2017-
Top 8% article
Muramatsu T, Kozaki KI, Imoto S, Yamaguchi R, Tsuda H, Kawano T, Fujiwara N, Morishita M, Miyano S, Inazawa J. The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma. Oncogene 2016, 35(40):5304-5316. Q1 journal
Minakuchi H, Sogawa C, Miki H, Hara ES, Maekawa K, Sogawa N, Kitayama S, Matsuka Y, Clark GT, Kuboki T. Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects. Sleep Breath 2016, 20(1):271-276.
Sogawa C, Ikegame M, Miyazaki I, Ara T, Imamura Y, Okusha Y, Ohyama K, Asanuma M, Sogawa N, Yamaomto T, Kozaki KI*. Changes in Metallothionein Isoform Expression in the Bones of Ovariectomized Rats. Journal of Hard Tissue Biology 2016, 25(1):21-26.
Review Articles 総説
Takanori Eguchi*, Takuo Kuboki. Cellular Reprogramming Using Defined Factors and MicroRNAs.
Stem Cells International 2016, 7530942:1-12
(2016 Journal Impact Factor =3.902) Q2 journal in cell & tissue engineering, 2015-
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Elsevier SciVal was used to calculate top 10% articles, Non-Field-Weighted Outputs in Top Citation Percentiles, per percentile.
Google Scholar was used to monitor the citations.
新たなチャレンジは私たちの原動力です。より良い研究開発と最善の教育を行うことが喜びであり、楽しくも真剣に取り組んでいます。